Special Topics:
Speech-Genetics

Shriberg, L. D. (1990, November). Speech assessment in familial disorders research. Paper presented in a miniseminar: Exploration of the Genetic Basis of Speech and Language Disorders, Annual Convention of the American Speech-Language-Hearing Association, Seattle, WA.

Shriberg, L. D. (1991, November). Towards a phenotype for developmental phonological disorders. Invited paper presented at Genetics: Progress and promise for communication sciences and disorders, American Speech-Language-Hearing Association, Atlanta, GA.

Shriberg, L. D. (1993). Four new speech and prosody-voice measures for genetics research and other studies in developmental phonological disorders. Journal of Speech and Hearing Research, 36, 105-140.

Shriberg, L. D. (1993, May). Phenotypes and phonologies: Facts and fictions. Paper presented at the 14th Annual Symposium on Research in Child Language Disorders, Madison, WI.

Lewis, B. A., & Shriberg, L. D. (1994, November). Life span interrelationships among speech, prosody-voice, and nontraditional phonological measures. Miniseminar presented at the Annual Convention of the American Speech-Language-Hearing Association, New Orleans, LA.

Flipsen, P., Jr., Shriberg, L. D., Weismer, G., Karlsson, H. B., & McSweeny, J. L. (1999). Acoustic characteristics of /s/ in adolescents. Journal of Speech, Language, and Hearing Research, 42, 663-677.

Tomblin, J. B., Shriberg, L. D., Nishimura, C., Zhang, X., & Murray, J. (1999, March). Association of Specific Language Impairment with Loci at 7q31. Poster presented at the Third International Symposium on Speech and Language Impairments: From Theory to Practice, York, United Kingdom.

Flipsen, P., Jr., Shriberg, L. D., Weismer, G., Karlsson, H. B., & McSweeny, J. L. (2001). Acoustic phenotypes for speech-genetics studies: Reference data for residual // distortions. Clinical Linguistics and Phonetics, 15, 603-630.

Lewis, B. A., Freebairn, L. A., Taylor, H. G., Hansen, A., Shriberg, L. D., Dawson, D. V., & Iyengar, S. (2001, November). Family pedigrees of children with suspected developmental apraxia of speech. Poster presented at the Annual Convention of the American Speech-Language-Hearing Association, New Orleans, LA.

Shriberg, L. D. (2001, June). Speech motor control processes in child speech disorders. Poster presented at the 4th International Speech Motor Conference, Nijmegen, the Netherlands.

Shriberg, L. D., Flipsen, P., Jr., Karlsson, H. B., & McSweeny, J. L. (2001). Acoustic phenotypes for speech-genetics studies: An acoustic marker for residual // distortions. Clinical Linguistics and Phonetics, 15, 631-650.

Karlsson, H. B., Shriberg, L. D., Flipsen, P., Jr., & McSweeny, J. L. (2002). Acoustic phenotypes for speech-genetics studies: Toward an acoustic marker for residual /s/ distortions. Clinical Linguistics and Phonetics, 16, 403-424.

Schick, J., Kundtz, A., Tiwari, H., Taylor, H., Freebairn, L., Hansen, A., Shriberg, L., Lewis, B. A., & Iyengar, S. K. (2002, May). Broad phenotype of speech disorders shows strong evidence of linkage at candidate region 7q31. Paper presented at the European Human Genetics Conference, Berlin, Germany.

Iyengar, S. (2003, November). Genetic analysis of speech sound disorders. Paper presented at the Annual Convention of the American Speech-Language-Hearing Association, Chicago, IL.

Karlsson, H. B., Shriberg, L. D., Scheer, A., & Nadler, C. J. (2003). Acoustic moments data for palatalized and dentalized sibilant productions from speech delayed children with and without histories of otitis media with effusion. (Tech. Rep. No. 12). Phonology Project, Waisman Center, University of Wisconsin-Madison.

Lewis, B. A., & Shriberg, L. D. (2003, November). Genetic research in speech sound disorders: Phenotype issues and recent findings. Paper presented at the Annual Convention of the American Speech-Language-Hearing Association, Chicago, IL.

Mills, C. E., Flipsen, P., Jr., Shriberg, L. D., Kwiatkowski, J., & McSweeny, J. L. (2003, November). Speech development in monozygotic and dizygotic twins with speech delay. Poster presented at the Annual Convention of the American Speech-Language-Hearing Association, Chicago, IL.

Shriberg, L. D. (2003, November). Phenotypes, endophenotypes, and phenocopies in speech-genetics research. Paper presented at the Annual Convention of the American Speech-Language-Hearing Association, Chicago, IL.

Smith, S. D., Deffenbacher, K. E., Boada, R., Tunick, R. A., Raitano, N., Shriberg, L. D., & Pennington, B. F. (2003, November). Speech sound disorder is linked to dyslexia risk loci on chromosome 6 and 15. Poster presented at the 53rd Annual Meeting of the American Society for Human Genetics, Los Angeles, CA.

Shriberg, L. D. (2004, February). Phenotype markers for genetically transmitted speech sound disorder. Paper presented at the 10th Symposium of the International Clinical Phonetics and Linguistics Association, Lafayette, LA.

Stein, C. M., Schick, J. H., Taylor, H. G., Shriberg, L. D., Millard, C., Kundtz-Kluge, A., Russo, K., Minich, N., Hansen, A., Freebairn, L. A., Elston, R. C., Lewis, B. A., & Iyengar, S. K. (2004). Pleiotropic effects of a chromosome 3 locus on speech-sound disorder and reading. American Journal of Human Genetics, 74, 284-297.

Raitano, N. A., Pennington, B. F., Tunick, R. A., Boada, R., & Shriberg, L. D. (2004). Pre-literacy skills of subgroups of children with speech sound disorders. Journal of Child Psychology and Psychiatry, 45, 821-835.

Shriberg, L. D. (2004, April). Childhood speech sound disorders. Paper presented at the University of Wisconsin-Madison Genetic Counseling Seminar, Madison, WI.

Shriberg, L. D. (2004, June). Classification research in childhood speech sound disorders of unknown origin: Gaining a foothold. Paper presented at the Alfred I. duPont Hospital, Wilmington, DE.

Lewis, B. A., Freebairn, L. A., Hansen, A., Taylor, H. G., Iyengar, S., & Shriberg, L. D. (2004). Family pedigrees of children with suspected childhood apraxia of speech. Journal of Communication Disorders, 37, 157-175.

Shriberg, L. D., Lewis, B. L., Tomblin, J. B., McSweeny, J. L., Karlsson, H. B., & Scheer, A. R. (2005). Toward diagnostic and phenotype markers for genetically transmitted speech delay. Journal of Speech, Language, and Hearing Research, 48, 834-852.

Smith, S. D., Pennington, B. F., Boada, R., & Shriberg, L. D. (2005). Linkage of speech sound disorder to reading disability loci. Journal of Child Psychology & Psychiatry, 46, 1057-1066.

Lewis, B. A., Freebairn, L. A., Hansen, A. J., Stein, C. M., Shriberg, L. D., Iyengar, S. K., & Taylor, H. G. (2006). Dimensions of early speech-sound disorders: A factor analytic study. Journal of Communication Disorders, 39, 139-157.

Lewis, B. A., Shriberg, L. D., Freebairn, L. A., Hansen, A. J., Stein, C. M., Taylor, H. G., & Iyengar, S. (2006). The genetic bases of speech sound disorders: evidence from spoken and written language. Journal of Speech, Language, and Hearing Research, 49, 1294-1312.

Shriberg, L. D., Ballard, K. J., Tomblin, J. B., Duffy, J. R., & Odell, K. H. (2006). Speech, prosody, and voice characteristics of a mother and daughter with a 7;13 translocation affecting FOXP2. Journal of Speech, Language, and Hearing Research, 49, 500-525.

Shriberg, L. D., Lohmeier, H. L., Dollaghan, C. A., & Campbell, T. F. (2006, May). A nonword repetition task for speakers with speech sound disorders: The Syllable Repetition Task. Paper presented at the 11th Meeting of the International Clinical Phonetics and Linguistics Association, Dubrovnik, Croatia.

Shriberg, L. D., Lohmeier, H. L., McSweeny, J. L., & Kwiatkowski, J. (2006, November). A nonword repetition task for speakers with misarticulations: The Syllable Repetition Task. Poster presented at the Annual Convention of the American Speech-Language-Hearing Association, Miami, FL.

Stein, C. M., Millard, C., Kluge, A., Miscimarra, L. E., Cartier, K. C., Freebairn, L. A., Hansen, A. J., Shriberg, L. D., Taylor, H. G., Lewis, B. A., & Iyengar, S. (2006). Speech sound disorder influenced by a locus in 15q14 region. Behavioral Genetics, 36, 858-868.

Miscimarra, L., Stein, C., Millard, C., Kluge, A., Cartier, K., Freebairn, L., Hansen, A., Shriberg, L., Taylor, H. G., Lewis, B., & Iyengar, S. (2007). Further evidence of pleitropy influencing speech and language: analysis of the DYX8 region. Human Heredity, 63, 47-58.

McGrath, L. M., Pennington, B. F., Willcutt, E. G., Shriberg, L. D., & Smith, S. D. (2007). Gene x environment interactions in speech sound disorder. Poster presented at the Society for Research in Child Development Biennial Meeting, Boston, MA.

McGrath, L. M., Pennington, B. F., Willcutt, E.G., Boada, R., Shriberg, L. D., & Smith, S.D. (2007). Gene x environment interactions in speech sound disorder predict language and pre-literacy outcomes. Development and Psychopathology, 19, 1047-1072.

McGrath, L. M., Hutaff-Lee, C., Scott, A., Boada, R., Shriberg, L. D., & Pennington, B. F. (2008). Children with comorbid speech sound disorder and specific language impairment are at increased risk for attention-deficit/hyperactivity disorder. Journal of Abnormal Child Psychology, 36, 151-163.

Shriberg, L. D., Jakielski, K. J., & El-Shanti, H. (2008). Breakpoint localization using array-CGH in three siblings with an unbalanced 4q:16q translocation and Childhood Apraxia of Speech (CAS). American Journal of American Genetics: Part A, 146A, 2227-2233.

Lewis, B. A. (November, 2008). Genetics of speech sound disorders and neurological correlates. Paper presented at the Annual Convention of the American Speech-Language-Hearing Association, Chicago, IL.

Maassen, B. (November, 2008). Modeling the development of Childhood Apraxia of Speech (CAS). Paper presented at the Annual Convention of the American Speech-Language-Hearing Association, Chicago, IL.

Robin, D. A. (November, 2008). The potential of non-invasive brain imaging in understanding CAS. Paper presented at the Annual Convention of the American Speech-Language-Hearing Association, Chicago, IL.

Shriberg, L. D., Lohmeier, H. L., Campbell, T. F., Dollaghan, C. A., Green, J. R., & Moore, C. A. (2009). A nonword repetition task for speakers with misarticulations: The Syllable Repetition Task (SRT). Journal of Speech, Language, and Hearing Research, 52, 1189-1212.

Tomblin, J.B., O'Brien, M., Shriberg, L.D., Williams, C., Murray, J., Patil, S., et al. (2009). Language features in a mother and daughter of a chromosome 7;13 translocation involving FOXP2. Journal of Speech, Language, and Hearing Research, 52, 1157-1174.

Shriberg, L. D. (October, 2009). Genetics and speech sound disorders: An etiology-based approach. Paper presented at the Van Riper Lectures, Western Michigan University, Kalamazoo, MI.

Shriberg, L. D. (July, 2009). Genetic and other research directions in Childhood Aparaxia of Speech. Paper presented at the 2009 National Conference on Childhood Apraxia of Speech, St. Charles, IL.

Shriberg, L. D. (2010). A neurodevelopmental framework for research in Childhood Apraxia of Speech. In B. Maassen & P. van Lieshout (Eds), Speech Motor Control: New developments in basic and applied research (pp. 259-270). Oxford: Oxford University Press.

Potter, N. L. (2011). Voice disorders in children with classic galactosemia. Journal of Inherited Metabolic Disease, 34, 377-385.

Stein, C. M., Lu, Q., Elston, R. C., Freebairn, L. A., Hansen, A. J., Shriberg, L. D., Taylor, H. G., Lewis, B. A., & Iyengar, S. K. (2011). Heritability estimation for speech-sound traits with developmental trajectories. Behavioral Genetics, 41, 184-191.

Rice, G.M., Raca, G., Jakielski, K., Laffin, J.J., Iyama-Kurtycz, C., Hartley, S.L., Shriberg, L.D. (March, 2011). Phenotypic characterization of the FOXP2 Haploinsufficiency. Poster presented at the American College of Medical Genetics Annual Meeting, Vancouver, British Columbia.

Shriberg, L. D. (June, 2011). Research trends in Childhood Apraxia of Speech. Paper presented at the 6th International Conference on Speech Motor Control, Groningen, the Netherlands.

Shriberg, L. D. (September, 2011). A neurodevelopmental framework for research in Childhood Apraxia of Speech. Paper presented at the Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands.

Raca, G., Laffin, J. J., Jackson, C., Jakielski, K. J., Strand, E. A., & Shriberg, L. D. (October, 2011). Identification of Genomic Copy Number Variants Associated with Childhood Apraxia of Speech (CAS). Paper presented at the 12th International Congress of Human Genetics and the 61st ASHG Annual Meeting, Montreal, Canada.

Shriberg, L. D. (December, 2011). Phenotype challenges in Childhood Apraxia of Speech and other Speech Sound Disorders. Paper presented at the 2nd Winter Institute, University of Hong Kong.

Baylis, A. L., & Shriberg, L. D. (July, 2012). Motor Speech Deficits in the 22q11.2 Deletion Syndrome. Paper to be presented at the 8th Biennial International 22q11.2 Conference, Orlando, FL.

Raca, G., Baas, B. S., Kirmani, S., Laffin, J. J., Jackson, C. A., Strand, E. A., Jakielski, K. J., & Shriberg, L. D. (2013). Childhood Apraxia of Speech (CAS) in two patients with 16p11.2 microdeletion syndrome. European Journal of Human Genetics, 21, 455-459.

Laffin, J. J. S., Raca, G., Jackson, C. A., Strand, E. A., Jakielski, K. J., & Shriberg, L. D. (2012). Novel candidate genes and regions for Childhood Apraxia of Speech (CAS) identified by array comparative genomic hybridization. Genetics in Medicine, 14, 928-936.

Baylis, A. L., Jensen, J. N., Kirschner, R. E., & Shriberg, L. D. (May, 2013). Motor Speech Deficits in 22q11.2 Deletion Syndrome. Paper presented at the 12th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies, Orlando, FL.

Worthey, E. A., Raca, G., Laffin, J. J., Wilk, B. M., Harris, J. M., Jakielski, K. J., Dimmock, D. P., Strand, E. A., & Shriberg, L. D. (2013). Whole exome sequencing supports genetic heterogeneity in Childhood Apraxia of Speech. Journal of Neurodevelopmental Disorders, 5, 29.

Shriberg, L. D., & Strand, E. A. (February, 2014). A Diagnostic Marker to Discriminate Childhood Apraxia of Speech from Speech Delay. Paper presented at the Seventeenth Biennial Conference on Motor Speech: Motor Speech Disorders & Speech Motor Control, Sarasota, FL.

Carrigg, B., Parry, L., Baker, E., Shriberg, L. D., & Ballard, K. (November, 2016). Persistent speech sound disorder outcomes in a multigenerational family. Paper presented at the Annual Convention of the American Speech-Language-Hearing Association, Philadelphia, PA.

Carrigg, B., Parry, L., Baker, E., Shriberg, L. D., & Ballard, K. J. (2016). Cognitive, linguistic, and motor abilities in a multigenerational family with Childhood Apraxia of Speech. Archives of Clinical Neuropsychology, doi: 10.1093/arclin/acw077. [Epub ahead of print].

Truong, D. T., Shriberg, L. D., Smith, S. D., Chapman, K. L., Scheer-Cohen, A. R., DeMille, M. M. C., Adams, A. K., Nato, A. Q., Wijsman, E. M., Eicher, J. D., & Gruen, J. R. (2016). Multipoint genome-wide linkage scan for nonword repetition in a multigenerational family further supports chromosome 13q as a locus for verbal trait disorders. Human Genetics, 135, 1329-1341.

Truong, D. T., Adams, A. K., DeMille, M. C. C., Smith, S. D., Shriberg, L. D., & Gruen, J. R. (July, 2017). Molecular genetic examination of nonword repetition in a multigenerational family with a history of verbal trait disorders. Poster presented at the Society for the Scientific Study of Reading Annual Meeting, Halifax, Nova Scotia, Canada.

Baylis, A. L., & Shriberg, L. D.(2018). Estimates of the prevalence of speech and motor speech disorders in youth with 22q11.2 Deletion syndrome. American Journal of Speech-Language Pathology. Advance online publication. doi: 10.1044/2018_AJSLP-18-0037.

Snijders Blok, L., and multiple authors (2018). CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language. Nature Communications, 9:4619. DOI: 10.1038/s41467-018-06014-6

Eising, E., Carrion-Castillo, A., Vino, A., Strand, E. A., Jakielski, K. J., Scerri. T. S., . . . Shriberg, L. D., Fisher, S. E. (2018). A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development. Molecular Psychiatry. Advance online publication. https://doi.org/10.1038/s41380-018-0020-x

Shriberg, L. D., Kwiatkowski, J., & Mabie, H. L. (2019). Estimates of the prevalence of motor speech disorders in children with idiopathic speech delay. Clinical Linguistics & Phonetics.

Shriberg, L. D., Strand, E. A., Jakielski, K. J., & Mabie, H. L. (2019). Estimates of the prevalence of speech and motor speech disorders in persons with complex neurodevelopmental disorders. Clinical Linguistics & Phonetics.

Shriberg, L. D., Campbell, T. F., Mabie H. L., & McGlothlin, J. H. (2019). Initial studies of the phenotype and persistence of Speech Motor Delay (SMD). Clinical Linguistics & Phonetics.

Shriberg, L. D., & Wren, Y. E. (2019). A frequent acoustic sign of Speech Motor Delay (SMD). Clinical Linguistics & Phonetics. doi:10.1080/02699206.2019.1595734. [Epub ahead of print]

Wilson, E. M., Abbeduto, L., Camarata, S. M., & Shriberg, L. D. (2019). Estimates of the prevalence of speech and motor speech disorders in adolescents with Down syndrome. Clinical Linguistics & Phonetics.

Wilson, E. M., Abbeduto, L., Camarata, S. M., & Shriberg, L. D. (2019). Speech and motor speech disorders and intelligibility in adolescents with Down syndrome. Clinical Linguistics & Phonetics.