Last updated June 7, 2018  

Family Adaptation to Fragile X Syndrome

Fragile X Syndrome Journal Articles

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Mailick, M.R., Movaghar, A., Hong, J., Greenberg, J.S., Smith Dawalt, L.E., Zhou, L., Jackson, J., Rathouz, P.J., Baker, M.W., Brilliant, M., Page, D., Berry-Kravis, E. (2018). Health Profiles of Mosaic Versus Non-mosaic FMR1 Premutation Carrier Mothers of Children With Fragile X Syndrome. Frontiers in Genetics, 9:173 doi:10.3389/fgene.2018.00173.

Laxman, D.J., Greenberg, J.S., Smith, L.E., Hong, J., Aman, M.G., & Mailick, M.R. (2018). Medication use by adolescents and adults with fragile X syndrome. Journal of Intellectual Disability Research, 62(2):94-105. doi:10.1111/jir.12433.

Movaghar A, Mailick M, Sterling A, Greenberg J, Saha K. (2017). Automated screening for Fragile X premutation carriers based on linguistic and cognitive computational phenotypes. Scientific Reports. 1;7(1):2674. doi:10.1038/s41598-017-02682-4.

Mailick, M.R., Hong, J., Greenberg, J., Smith Dawalt, L.E., Baker, M.W., Rathouz, P.J. (2017). FMR1 genotype interacts with parenting stress to shape health and functional abilities in older age. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 9999:1-14.

Chan, W., Smith, L.E., Greenberg, J.S., Hong, J., & Mailick, M.R. (2017). Executive functioning mediates the effect of behavioral problems on depression in mothers with children with developmental disabilities. American Journal of Intellectual and Developmental Disabilities, 122(1): 11-24; doi: 10.1352/1944-7558-122.1.11.PMCID:PMC5303617

Wheeler A, Raspa M, Hagerman R, Mailick MR, Riley C. (2017). Implications of the FMR1 premutation for children, adolescents, adults, and their families. Pediatrics, 129 (s3):s172-s182. doi: 10.1542/peds.2016-1159D.

Smith, L. E., Hong, J., Greenberg, J. S., & Mailick, M. R. (2016). Change in the behavioral phenotype of adolescents and adults with FXS: Role of the family environment. Journal of Autism and Developmental Disorders, 46(5):1824-33. doi: 10.1007/s10803-016-2714-8.

Mailick, M.R., Hong, J., Greenberg, J., Smith, L., & Sherman, S. (2014). Curvilinear association of CGG repeats and age at menopause in women with FMR1 premutation expansions. American Journal of Medical Genetics Part B Neuropsychiatric Genetics, 165(8):705-11. doi:10.1002/ajmg.b.32277

Wheeler, A.C., Bailey, D.B., Jr, Berry-Kravis, E., Greenberg, J., Losh, M., Mailick, M, Milà, M., Olichney, J.M., Rodriguez-Revenga, L., Sherman, S., Smith, L., Summers, S., Yang, J.C., & Hagerman, R. (2014). Associated features in females with an FMR1 premutation. Journal of Neurodevelopmental Disorders, 6(1):30. doi:10.1186/1866-1955-6-30

Mailick, M.R., Hong, J., Rathouz, P., Baker, M.W., Greenberg, J.S., Smith, L., & Maenner, M. (2014) Low-normal FMR1 CGG repeat length: phenotypic associations. Frontiers in Genetics. 9;5:309. doi:10.3389/fgene.2014.00309

Wong, J.D., Mailick, M.R., Greenberg, J.S., Hong, J., & Coe, C.L. (2014). Daily work stress and awakening cortisol in mothers of individuals with and without autism spectrum disorders or fragile X syndrome. Family Relations. 63(1): 135–147 135. doi:10.1111/fare.12055

Sterling, A., Mailick, M.R., Greenberg, J.S., Warren, S.F., & Brady, N. (2013). Language dysfluencies in females with the FMR1 premutation. Brain and Cognition. 82(1):84-9. doi:10.1016/j.bandc.2013.02.009

Maenner, M.J., Baker, M.W., Broman, K.W., Tian, J., Barnes, J.K., Atkins, A., McPherson, E., Hong, J., Brilliant, M.H., Mailick, M.R. (2013). FMR1 CGG expansions: prevalence and sex ratios. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 162B(5), 466-73. doi:10.1002/ajmg.b.32176

Hartley, S., Seltzer, M.M., Head, L., & Abbeduto, L. (2012). Psychological well-being in fathers of adolescents/young adults with Down syndrome, fragile X syndrome, and autism. Family Relations, 61(2):327-342. PMID:22611299; PMCID:PMC33452598 [Available on 2013/4/1]

Seltzer MM, Baker MW, Hong J, Maenner M, Greenberg J, Mandel D. (2012) Prevalence of CGG expansions of the FMR1 gene in a US population-based sample. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 159(5), 589-97. doi:10.1002/ajmg.b.32065

Greenberg, J.S., Seltzer, M.M., Baker, J., Smith, L., Warren, S., Brady, N., Hong, J. (2012). Family environment and behavior problems in children, adolescents, and adults with fragile x syndrome. American Journal of Intellectual and Developmental Disabilities, 117(4), 331-46. doi:10.1352/1944-7558-117.4.331

Baker, J.K., Seltzer, M.M., & Greenberg, J.S. (2012). Behavior problems, maternal internalizing symptoms, and family relations in families of adolescents and adults with fragile X syndrome. Journal of Intellectual Disability Research, 56(10), 984–995. doi:10.1111/j.1365-2788.2012.01580.x

Seltzer, M.M., Barker, E.T., Greenberg, J.S., Hong, J., Coe, C., & Almeida, D. (2012). Differential sensitivity to life stress in FMR1 premutation carrier mothers of children with fragile X syndrome. Health Psychology, 31(5), 612-22. doi:10.1037/a0026528

Smith, L. E., Barker, E. T., Seltzer, M. M., Abbeduto, L., & Greenberg, J. S. (2012). Behavioral phenotype of fragile x syndrome in adolescence and adulthood. American Journal on Intellectual and Developmental Disabilities,117(1), 1-17. doi:10.1352/1944-7558-117.1.1

Smith, L. E., Seltzer, M. M., & Greenberg, J. S. (2012). Daily health symptoms of mothers of adolescents and adults with fragile X syndrome and mothers of adolescents and adults with autism spectrum disorder. Journal on Autism and Developmental Disorders, 42(9), 1836-46. doi:10.1007/s10803-011-1422-7

Hartley, S.L., Seltzer, M.M., Hong, J., Greenberg, J.S., Almeida, D., Coe, C., & Abbeduto, L. (2011). Cortisol response to behavior problems in FMR1 Premutation mothers of adolescents and adults with fragile X syndrome: A diathesis-stress model. International Journal of Behavioral Development, 36(1), 53–61. doi:10.1177/0165025411406857

Hartley, S.L., Seltzer, M.M., Raspa, M., Olmsted, M.G. Bishop, E.E., & Bailey, D.B. (2011). Exploring the adult life of men and women with fragile X syndrome: Results from a national survey. American Journal of Intellectual and Developmental Disabilities, 116(1), 16-35. doi:10.1352/1944-7558-116.1.16

Abbeduto, L., Seltzer, M.M., Shattuck, P., Krauss, M.W., Orsmond, G., & Murphy, M.M. (2004). Psychological well-being and coping in mothers of youths with autism, Down syndrome, or fragile X syndrome. American Journal of Mental Retardation, 109(3), 237-254. doi:10.1352/0895-8017(2004)109<237:PWACIM>2.0


Fragile X Syndrome Book Chapters

Cultural and contextual perspectives on development at riskMailick, M.R., Greenberg, J.S., Smith, L., Sterling, A., Brady, N., Warren, S.F., Hong, J. (2014). Fragile X-associated disorders: How the family environment and genotype interact, p 221-253. In Burack, J., & Schmidt, L. Cultural and contextual perspectives on development at risk, Cambridge: Cambridge University Press

Book cover

Seltzer, M.M., Abbeduto, L., Greenberg, J.S., Almeida, D., Hong, J., & Witt, W. (2009). Biomarkers in the study of families of children with developmental disabilities. (pp. 213-250). In L. M. Glidden and M. M. Seltzer (Eds). International Review of Research on Mental Retardation, 37. New York: Academic Press.

book coverEsbensen, A.J., Seltzer, M.M., & Abbeduto, L. (2007). Family well-being in Down syndrome and fragile X syndrome. In J. E. Roberts, R. Chapman, & S. Warren (Eds.), Speech and language development and intervention in Down syndrome and fragile X syndrome (pp. 275-295). Baltimore, MD: Brookes.




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